Home' Australian Pharmacist : Australian Pharmacist May 2012 Contents Australian Pharmacist May 2012 I ©Pharmaceutical Society of Australia Ltd. 407
Continuing Professional Development
Submit your answers online at www.psa.org.au and receive automatic feedback
Knowledge in practice
Through successful completion of this
activity, the learner will demonstrate
their ability to:
• Use readily available information
sources to access and select relevant
and up-to-date clinical and practice-
• Promote and contribute to the
optimal use of medicines
• Address primary health needs
Competency standards (2010)
addressed: 4.2.1, 4.2.2, 4.2.3, 6.1.1,
6.1.2, 7.1.2, 7.1.3, 7.1.4, 7.2.2
To answer Knowledge in practice
Answers for Knowledge in practice can
only be submitted online through the PSA
members-only area of the PSA website
at: www.psa.org.au PSA members will
receive instant feedback on the correct
answers with an explanation of why the
answer is correct. If you do not have
member access details for the PSA website,
you can request them via a link from the
Question 1. Ventricular
Mr JD, a 53-year-old marketing executive,
comes into the pharmacy intermittently
for seasonal asthma and the occasional
cold and u medicine or analgesic. He
exercises regularly and has no other
health complaints. Today Mr JD comes
in looking concerned. 'I've just been to
the doctor for a routine check-up and,
although I feel ne, the doctor said I
have a funny heart rhythm. He called
it premature ventricular ectopics, or
some funny initials -- VBPs, and said my
heart was throwing in an extra beat. He
said I shouldn't be too worried about
it, and that cutting down on co ee and
alcohol may help to reduce the extra
beats. However, when he saw I was
really concerned, because dad died
from a funny heartbeat -- AF I think they
called it -- he gave me this.' He gives
you a prescription for amiodarone 200
mg tablets with standard oral loading
dose instructions (as per the Australian
Medicines Handbook) leading into a
maintenance dose of 200 mg daily.
Which of the following is the MOST
APPROPRIATE course of action for you
a) Call the GP and recommend changing
the amiodarone to ecainide since
JD has a history of asthma, and
amiodarone can worsen lung function.
b) Call the GP and recommend that JD
also be prescribed aspirin, as he is at
increased risk of a blood clot due to
stasis of blood within his ventricles.
c) Call the GP and recommend changing
the amiodarone to atenolol, because
beta-blockers are the drugs of choice
for ventricular ectopic beats.
d) Call the GP and recommend
reconsidering the need for therapy,
since ventricular ectopic beats are
usually benign, and antiarrhythmics
have many signi cant potential
adverse e ects.
Question 2. A dose calculation
Additional reference: International Atomic
Energy Agency (IAEA). Calculation of the
volume of eluate required. IAEA Human
Health Campus. At: http://tinyurl.com/
Please note: you will need a scienti c
calculator to assist you with this question.
An online scienti c calculator can be
found at: http://web2.0calc.com/
You are a pharmacist working in a
radiopharmaceutical facility at a large
hospital. The clinicians are using a new
isotope, Imagium, for radioiosotope
scans. The half-life of Imagium is 8.4
You measured the activity of your
Imagium generator at 9am today and the
activity was 1267 MBq/mL.
It is now 2:15pm and you need to elute
an appropriate volume of Imagium to
provide a dose of 500 MBq for a patient
who will have the dose administered
today at 4:45pm. As is good practice, you
always allow a 10% excess in the dose.
Which of the following is the correct
volume to elute from your generator at
(Please note: if the answer to your
calculation does not match one of these
answers, check your calculation again
rather than estimating to the closest
a) 0.80 mL.
b) 1.06 mL.
c) 0.75 mL.
d) 0.82 mL.
(Each questions is worth 0.5 CPD Credits.)
The challenge of applying what you
learn to pharmacy practice!
Knowledge in practice is designed
to be di cult and aims to make you
apply information from articles in
this month's Australian Pharmacist
and other suggested reading to the
questions below, just as you would
for a client/patient. This section is not
meant to be easy. There are no simple
clear-cut answers to the questions.
The standard references listed below
may be of use when answering
1. Sansom L (ed). Australian Pharmaceutical Formulary and
Handbook, 22nd Ed. Canberra: Pharmaceutical Society of
2. Rossi S (ed). Australian Medicines Handbook. Adelaide:
Australian Medicines Handbook Pty Ltd; 2012.
3. National Prescribing Service [online]. At: www.nps.org.au
4. Merck Manual of Diagnosis and Therapy [online].
5. Product information -- available from various sources, e.g.
MIMS, APP Guide or online on manufacturers' websites.
6. Royal College of Pathologists of Australasia. RCPA Manual
[online]. At: www.rcpamanual.edu.au
7. Therapeutic Guidelines Series. eTG complete [CD-ROM].
Melbourne: Therapeutic Guidelines Limited.
KNOWLEDGE IN PRACTICE
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