Home' Australian Pharmacist : Australian Pharmacist November 2012 Contents 906 Australian Pharmacist November 2012 I ©Pharmaceutical Society of Australia Ltd.
Continuing Professional Development
Through successful completion of this
activity, the learner will demonstrate
their ability to:
• Use readily available information
sources to access and select
relevant and up-to-date clinical and
• Promote and contribute to the
optimal use of medicines
• Address primary health needs
Competency standards (2010)
addressed: 4.2.1, 4.2.2, 4.2.3, 6.1.1,
6.1.2, 7.1.2, 7.1.3, 7.1.4, 7.2.2.
Accreditation number: CAP121111g
To answer Knowledge in practice
Answers for Knowledge in practice
can only be submitted online through
the PSA members-only area of the
PSA website at: www.psa.org.au
PSA members will receive instant
feedback on the correct answers with
an explanation of why the answer is
correct. If you do not have member
access details for the PSA website, you
can request them via a link from the
The challenge of applying what you
learn to pharmacy practice!
Knowledge in practice is designed
to be difficult and aims to make you
apply information from articles in this
month's Australian Pharmacist and other
suggested reading to the questions
below, just as you would for a client/
patient. This section is not meant to
be easy. There are no simple clear-cut
answers to the questions. The standard
references listed below may be of use
when answering the questions.
1. Sansom L (ed). Australian Pharmaceutical Formulary
and Handbook, 22nd Ed. Canberra: Pharmaceutical
Society of Australia, 2012.
2. Rossi S (ed). Australian Medicines Handbook.
Adelaide: Australian Medicines Handbook Pty Ltd;
3. National Prescribing Service [online]. At: www.nps.
4. Merck Manual of Diagnosis and Therapy [online].
5. Product information -- available from various
sources, e.g. MIMS, APP Guide or online on
6. Royal College of Pathologists of Australasia. RCPA
Manual [online]. At: www.rcpamanual.edu.au
7. Therapeutic Guidelines Series. eTG complete [CD-
ROM]. Melbourne: Therapeutic Guidelines Limited.
Additional reference: Australian Government Department of Health and Ageing.
The Australian Immunisation Handbook 9th edition. At: http://tinyurl.com/
Which of the following statements
regarding pertussis prophylaxis is
a) An appropriate post-exposure
pertussis prophylaxis regimen for
a 5-month-old infant (6.5 kg) is
azithromycin oral liquid 2.6 mL daily
for five days.
b) An 18-month-old fully-vaccinated
child who attends regular childcare
with another child of the same age
who has recently been diagnosed
with pertussis should receive a DTPa
booster dose as soon as possible.
c) A 30-year-old legal secretary who
has recently discovered that she is
pregnant with her first child should
receive a dose of dTpa as soon as
d) A 6-month-old infant who received
DTPa vaccines at eight and 16 weeks
of age and a third dose 4 days ago,
and who has just been exposed
to pertussis at childcare for 1 day,
should receive a 5-day course of
chemoprophylaxis before returning to
Additional reference: NPS. Depression. Prescribing Practice Review 58. 2012. At:
Mrs Tapper (70 years, 156 cm, 49 kg,
medium frame) has been to her GP
who has prescribed venlafaxine 150
mg daily for moderate--severe major
depression. Mrs Tapper has had three
prior episodes of major depression.
She also has severe osteoporosis and
osteoarthritis in her back, for which she
is taking risedronate 150 mg once a
month, paracetamol 1330 mg three times
a day and oxycodone (controlled release)
20 mg twice daily. Six years ago, she
was diagnosed with Parkinson's disease
which is well-controlled with pramipexole
1.5 mg daily and selegiline 7.5 mg twice
daily. She also takes ramipril 10 mg daily
for hypertension. Her most recent blood
pressure measurement was 145/85.
Recent pathology results (last week)
included the following:
• Na: 133 mmol/L (135-145)
• Cr: 175 micromol/L (50-110)
• Liver function tests: no abnormalities.
Which of the following statements
regarding Mrs Tapper's
antidepressant therapy is MOST
a) Sertraline is preferred over venlafaxine
for Mrs Tapper because of the risk of
b) Agomelatine is the preferred
antidepressant for Mrs Tapper and, if
effective, should be continued for at
least 24 months.
c) Venlafaxine is preferred over sertraline
because it is less likely to affect Mrs
Tapper's blood pressure.
d) Venlafaxine is an appropriate
antidepressant for Mrs Tapper, but the
starting dose should be reduced to
75 mg daily.
Knowledge in practice
Question 1. Pertussis
KNOWLEDGE IN PRACTICE
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